Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PPIA | P62937 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952615 | 0.84 | POLB (0.56) | POLBPPIANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2211898 | 0.82 | CYP1A2 (0.48) | POLBNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29956252 | 0.80 | POLB (0.51) | POLBNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL29950689 | 0.79 | NPC1 (0.64) | POLBNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28110815 | 0.77 | TRIM24 (0.42) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL18640773 | 0.77 | POLB (0.65) | POLBNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3713256 | 0.77 | TRIM24 (0.47) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL4138173 | 0.77 | ALDH1A1 (0.44) | POLBPPIANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29957414 | 0.75 | POLB (0.59) | POLBNPC1RAB9ALMNANAMPT | |
| SCHEMBL29950651 | 0.75 | POLB (0.59) | POLBNPC1RAB9ALMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |