Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 7/20 | 0.41 |
| ▸ | DHPS | P49366 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954152 | 0.88 | HTT (0.43) | HTTMAPTMEN1KMT2AIDH1 | |
| SCHEMBL2558098 | 0.85 | PARP1 (0.41) | HTTMAPTMEN1KMT2ADHPS | |
| SCHEMBL29956559 | 0.84 | HRH3 (0.40) | HTTMAPTMEN1KMT2ADHPS | |
| SCHEMBL12164213 | 0.79 | MEN1 (0.45) | HTTMAPTMEN1KMT2AIDH1 | |
| SCHEMBL29951975 | 0.79 | POLB (0.38) | HTTMEN1KMT2APOLB | |
| SCHEMBL23350137 | 0.78 | MAPK1 (0.48) | HTTMAPTMEN1KMT2AIDH1 | |
| SCHEMBL21025963 | 0.78 | IDH1 (0.43) | HTTMAPTMEN1KMT2AIDH1 | |
| SCHEMBL1949749 | 0.78 | BRD4 (0.44) | HTTMAPTMEN1KMT2AIDH1 | |
| SCHEMBL17050405 | 0.75 | IDH1 (0.47) | HTTMAPTMEN1KMT2AIDH1 | |
| SCHEMBL24761863 | 0.75 | HRH3 (0.45) | HTTMAPTMEN1KMT2AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |