Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | UGCG | Q16739 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558098 | 0.80 | PARP1 (0.41) | LMNAPARP1MEN1HTTKMT2A | |
| SCHEMBL29954152 | 0.80 | HTT (0.43) | LMNAPARP1ALDH1A1MEN1HTT | |
| SCHEMBL29951946 | 0.79 | IDH1 (0.44) | POLBALDH1A1MEN1HTTKMT2A | |
| SCHEMBL29957027 | 0.79 | HTT (0.44) | POLBMEN1HTTKMT2A | |
| SCHEMBL29951234 | 0.79 | NOTUM (0.45) | ALDH1A1SMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL19370098 | 0.79 | CRBN (0.48) | POLBRECQLLMNAPARP1ALDH1A1 | |
| SCHEMBL29951915 | 0.78 | UGCG (0.58) | LMNASMN1; SMN2UGCGMEN1HTT | |
| SCHEMBL1333882 | 0.77 | PIM1 (0.46) | POLBRECQLPARP1ALDH1A1UGCG | |
| SCHEMBL17520009 | 0.77 | ALDH1A1 (0.46) | POLBRECQLPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18368411 | 0.76 | KCNJ1 (0.38) | POLBRECQLLMNAPARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |