Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DHPS | P49366 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957027 | 0.84 | HTT (0.44) | HRH3DHPSHTTMEN1MAPT | |
| SCHEMBL29954152 | 0.81 | HTT (0.43) | HRH3DHPSHTTMEN1MAPT | |
| SCHEMBL2558098 | 0.81 | PARP1 (0.41) | HRH3DHPSHTTMEN1MAPT | |
| SCHEMBL29957144 | 0.77 | PARP1 (0.42) | PREPHTTALOX15LMNAALDH1A1 | |
| SCHEMBL29951975 | 0.75 | POLB (0.38) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29951946 | 0.72 | IDH1 (0.44) | HTTMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL29951234 | 0.72 | NOTUM (0.45) | HTTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29951915 | 0.71 | UGCG (0.58) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL24761863 | 0.69 | HRH3 (0.45) | HRH3DHPSHTTMEN1MAPT | |
| SCHEMBL29953994 | 0.69 | KDM4E (0.37) | PREPENPP2DPP4FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |