Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956203 | 0.88 | ERN1 (0.42) | ERN1CTSVCTSLKDM4EPOLB | |
| SCHEMBL29955999 | 0.84 | TNKS2 (0.40) | ERN1KDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL15331116 | 0.84 | ERN1 (0.40) | ERN1SMN1; SMN2 | |
| SCHEMBL2555909 | 0.82 | ERN1 (0.38) | ERN1KDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL29954488 | 0.80 | SMN1; SMN2 (0.44) | MAPTKMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL15331877 | 0.79 | ERN1 (0.38) | ERN1KDM4EPOLBMAPTGRIN2D | |
| SCHEMBL29951627 | 0.79 | MAPT (0.38) | ERN1CTSVCTSLMAPTKMT2A | |
| SCHEMBL29952426 | 0.78 | LMNA (0.40) | ERN1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL29951490 | 0.78 | PARP1 (0.43) | CTSVCTSLGPR17PARP1 | |
| SCHEMBL15332851 | 0.78 | ERN1 (0.38) | ERN1KDM4EPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |