Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL3006069 | 1.00 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL11586569 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL3148612 | 0.94 | NFKB1 (0.36) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL3145323 | 0.94 | NFKB1 (0.36) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL6664381 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL2171867 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL11585256 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL3748789 | 0.86 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL5088800 | 0.86 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL311124 | 0.86 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226807-A1 | Polymer Composites and Methods of Making the Same | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2023-07-20 | — | — | US | disclosed |
| WO-2021226424-A1 | POLYMER COMPOSITES AND METHODS OF MAKING THE SAME | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-3436537-B1 | ANAEROBICALLY CURABLE (METH)ACRYLATE COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2021-09-29 | — | — | EP | disclosed |
| US-11111416-B2 | Anaerobically curable (meth)acrylate compositions | Henkel IP & Holding GmbH (DE) | 2021-09-07 | — | — | US | disclosed |
| EP-3402855-B1 | CURE OF ANAEROBIC COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2021-07-14 | — | — | EP | disclosed |
| US-10414948-B2 | Cure of anaerobic compositions | Henkel IP & Holding GmbH (DE) | 2019-09-17 | — | — | US | disclosed |
| US-20190031921-A1 | ANAEROBICALLY CURABLE (METH)ACRYLATE COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2019-01-31 | — | — | US | disclosed |
| US-20180320027-A1 | CURE OF ANAEROBIC COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2018-11-08 | — | — | US | disclosed |
| US-9382179-B2 | Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150160149-A1 | SENSING MATERIAL FOR GAS SENSOR, GAS SENSOR COMPRISING THE SENSING MATERIAL, METHOD OF PREPARING THE SENSING MATERIAL, AND METHOD OF MANUFACTURING THE GAS SENSOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-06-11 | — | — | US | disclosed |
| US-20140303404-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2014-10-09 | — | — | US | disclosed |
| US-8785697-B2 | Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals | EASTMAN CHEMICAL COMPANY (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120330068-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | EASTMAN CHEMICAL COMPANY (US) | 2012-12-27 | — | — | US | disclosed |
| US-8293938-B2 | Alkylphosphonous acids, salts and esters, methods for the production thereof, and use of the same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-10-23 | — | — | US | disclosed |
| US-20100190901-A1 | Alkylphosphonous Acids, Salts and Esters, Methods for the Production Thereof, and Use of the Same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330068-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | KAT5, HRH3, KAT8 | NFKB1 1348/4885TSHR 4345/4885CA12 955/4885 |
| US-20140303404-A1 | NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS | KAT5, HRH3, KAT8 | NFKB1 1348/4885TSHR 4345/4885CA12 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.