Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL1933445 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL9807450 | 1.00 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL11467285 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL7723894 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL3748789 | 0.86 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL2995717 | 0.86 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL5088800 | 0.86 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL6664381 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL11586569 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL11585256 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085197-A | Synthesis method of 4- (3-trifluoromethylphenyl) -1-piperazine-ethanol, flibanserin intermediate and flibanserin | 合肥创新医药技术有限公司 | 2022-02-25 | — | — | CN | claimed |
| US-8940197-B2 | Processes for producing palladium nanoparticle inks | XEROX CORPORATION (US) | 2015-01-27 | — | — | US | claimed |
| US-20130221288-A1 | PROCESSES FOR PRODUCING PALLADIUM NANOPARTICLE INKS | XEROX CORPORATION (US) | 2013-08-29 | — | — | US | claimed |
| US-20240360562-A1 | METHOD FOR MANUFACTURING COMPOSITE MATERIAL TO BE PLATED AND METHOD FOR MANUFACTURING ANISOTROPIC ELECTROCONDUCTIVE SHEET | MITSUI CHEMICALS, INC. (JP) | 2024-10-31 | — | — | US | disclosed |
| WO-2024162230-A1 | CLEANING LIQUID, METHOD FOR PRODUCING MATERIAL TO BE PLATED USING SAME, AND METHOD FOR PRODUCING ANISOTROPIC CONDUCTIVE SHEET | 三井化学株式会社 | 2024-08-08 | — | — | WO | disclosed |
| CN-114085197-A | Synthesis method of 4- (3-trifluoromethylphenyl) -1-piperazine-ethanol, flibanserin intermediate and flibanserin | 合肥创新医药技术有限公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-2653503-B1 | METHOD FOR PRODUCING A COMPOSITE CURED PRODUCT | TORAY INDUSTRIES (JP) | 2018-11-21 | — | — | EP | disclosed |
| US-10005905-B2 | Molding material, prepreg, fiber-reinforced composite material, fiber-reinforced composite material laminate, and process for production of fiber-reinforced molding base material | TORAY INDUSTRIES, INC. (JP) | 2018-06-26 | — | — | US | disclosed |
| EP-3159435-B1 | ADDITIVE FOR SILVER PALLADIUM ALLOY ELECTROLYTES | UMICORE GALVANOTECHNIK GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |
| EP-3159435-A1 | ADDITIVE FOR SILVER PALLADIUM ALLOY ELECTROLYTES | Umicore Galvanotechnik GmbH (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-9340672-B2 | Resin composition, composite cured product using same, and method for producing the composite cured product | TORAY INDUSTRIES, INC. (JP) | 2016-05-17 | — | — | US | disclosed |
| US-5380906-A | Platinum group metal ion exchanged zeolite catalyst | UBE INDUSTRIES, LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0627381-A1 | PROCESS FOR PRODUCING HYDROGEN PEROXIDE | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0559212-A1 | Process for preparing carbonic diester | UBE INDUSTRIES, LTD. (JP) | 1993-09-08 | — | — | EP | disclosed |
| EP-0126617-B1 | MACROMOLECULE DETERMINATION BY PHSYSICAL DEVELOPMENT | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0192463-B1 | STABILIZATION OF DEVELOPED ELECTROPHOREGRAMS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-05-02 | — | — | EP | disclosed |
| US-4672043-A | PALLADIUM TETRAMINE SALT, DIMETHYLAMINE BORANE, NICKEL CHLORIDE, TETRAZOLIUM SALT | EASTMAN KODAK COMPANY (US) | 1987-06-09 | — | — | US | disclosed |
| EP-0192463-A2 | Stabilization of developed electrophoregrams | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-08-27 | — | — | EP | disclosed |
| US-4552848-A | PALLADIUM TETRAAMMINE SALT, DIMETHYLAMINE BORANE, POLYACRYLAMIDE G | EASTMAN KODAK COMPANY (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0126617-A2 | Macromolecule determination by phsysical development | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-11-28 | — | — | EP | disclosed |