SCHEMBL531660

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2925357	0.88	ALDH1A1 (0.53)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL2561787	0.86	ALDH1A1 (0.64)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL2555859	0.85	MEN1 (0.61)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL2555161	0.84	ALDH1A1 (0.59)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL29957232	0.84	ALDH1A1 (0.66)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL11785719	0.83	PLA2G4B (0.53)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL15330441	0.83	MAPT (0.53)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL4173816	0.82	MAPT (0.51)	ALDH1A1LMNAMAPTHPGDSMN1; SMN2
	SCHEMBL10504393	0.82	PTGS2 (0.54)	ALDH1A1LMNAMAPTSMN1; SMN2HTT
	SCHEMBL2557303	0.82	MAPT (0.52)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.