Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | ADK | P55263 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623510 | 1.00 | NISCH (0.55) | NISCHMTORADKCDK8AXL | |
| SCHEMBL12651457 | 0.92 | NISCH (0.54) | NISCHMTORADKCDK8AXL | |
| SCHEMBL12607523 | 0.86 | NISCH (0.50) | NISCHMTORADKCDK8AXL | |
| SCHEMBL16777437 | 0.82 | NISCH (0.72) | NISCHMTORADKVCPALDH1A1 | |
| SCHEMBL8671665 | 0.79 | NISCH (0.54) | NISCHMTORADKCDK8AXL | |
| SCHEMBL1458811 | 0.79 | NISCH (0.58) | NISCHMTORADKALDH1A1KDM4E | |
| SCHEMBL6470451 | 0.77 | NISCH (0.47) | NISCHMTORADKVCPALDH1A1 | |
| SCHEMBL6470455 | 0.77 | NISCH (0.47) | NISCHMTORADKVCPALDH1A1 | |
| SCHEMBL7984072 | 0.76 | VCP (0.52) | NISCHMTORADKVCPALDH1A1 | |
| SCHEMBL6470431 | 0.76 | HDAC1 (0.62) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |