Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFSF11 | O14788 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23114 | 0.83 | ENPP2 (0.52) | TSHRALDH1A1PTGS1BACE1POLB | |
| SCHEMBL16346292 | 0.78 | TNFSF11 (0.41) | TNFSF11TSHRNR3C1RAB9AKDM4E | |
| SCHEMBL29954912 | 0.78 | SMN1; SMN2 (0.48) | TSHRRAB9AKDM4EALDH1A1GAA | |
| SCHEMBL20943078 | 0.77 | HTT (0.46) | TSHRKDM4EALDH1A1GAACYP1A2 | |
| SCHEMBL6196237 | 0.77 | TNFSF11 (0.56) | TNFSF11TSHRNR3C1RAB9AKDM4E | |
| SCHEMBL3327344 | 0.77 | CA12 (0.63) | TNFSF11TSHRNR3C1RAB9AKDM4E | |
| SCHEMBL28818319 | 0.76 | ALDH1A1 (0.42) | TSHRKDM4EALDH1A1GAACYP1A2 | |
| SCHEMBL30016565 | 0.76 | MKNK1 (0.48) | KDM4EALDH1A1GAACA1CA2 | |
| SCHEMBL27836294 | 0.75 | TSHR (0.56) | TNFSF11TSHRNR3C1RAB9AKDM4E | |
| SCHEMBL11401919 | 0.75 | TNFSF11 (0.55) | TNFSF11TSHRNR3C1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |