SCHEMBL29957293

SCHEMBL29957293

[C-]#[N+]Cc1cc(F)cc(F)c1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
DAO P14920 1/20 0.31
DBH P09172 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408504 0.80
SCHEMBL29951474 0.77 TAAR1 (0.50) IDO1
SCHEMBL5672968 0.76 IDO1 (0.48) IDO1
SCHEMBL5323233 0.69 IDO1 (0.46) IDO1CA12CA1CA9DAO
SCHEMBL29956731 0.69 HTT (0.41) DAO
SCHEMBL29954604 0.69 IDO1 (0.47) IDO1DAO
SCHEMBL12629117 0.68 PGK1 (0.38)
SCHEMBL29954468 0.68 IDH1 (0.35)
SCHEMBL10204783 0.68 IDO1 (0.39) IDO1
SCHEMBL5251885 0.67 IDO1 (0.50) IDO1CA12CA1CA9DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed