SCHEMBL1408504

SCHEMBL1408504

[C-]#[N+]Cc1cc(C[N+]#[C-])cc(C[N+]#[C-])c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL407367 0.82 DHFR (0.39)
SCHEMBL9144039 0.76 ALDH1A1 (0.52)
SCHEMBL12869579 0.72 KDM4E (0.34)
SCHEMBL12752348 0.72 GRM5 (0.34)
SCHEMBL9142784 0.71 PTGS2 (0.57)
SCHEMBL12374395 0.67 ALDH1A1 (0.50)
SCHEMBL4890253 0.67 IDO1 (0.46)
SCHEMBL3890376 0.67 TAAR1 (0.42)
SCHEMBL5452057 0.67 TAAR1 (0.50)
SCHEMBL12445232 0.63 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344096-B2 Phosphorus-containing polycarbonate polyol, method for production thereof, and phosphorus-containing polycarbonate polyurethane UBE INDUSTRIES, LTD. (JP) 2013-01-01 US disclosed
EP-1806378-B1 Polythiourethane UBE INDUSTRIES (JP) 2011-10-12 EP disclosed
EP-1743912-B1 POLYTHIOURETHANE UBE INDUSTRIES (JP) 2011-03-09 EP disclosed
US-20100197887-A1 PHOSPHORUS-CONTAINING POLYCARBONATE POLYOL, METHOD FOR PRODUCTION THEREOF, AND PHOSPHORUS-CONTAINING POLYCARBONATE POLYURETHANE UBE INDUSTRIES, LTD. (JP) 2010-08-05 US disclosed
US-7544761-B2 Polythiourethane UBE INDUSTRIES, LTD. (JP) 2009-06-09 US disclosed
US-7385022-B2 Polythiocarbonate polythiol UBE INDUSTRIES, LTD. (JP) 2008-06-10 US disclosed
US-20080058477-A1 having a high refractive index and low dispersion which is obtained through a reaction between a polythiol component containing one or more polythiocarbonate polythiol and a polyisocyanate component containing a polyisocyanate and/or a polyisothiocyanate UBE INDUSTRIES, LTD. A CORPORATION 1978-96 (JP) 2008-03-06 US disclosed
EP-1806378-A2 Polythiourethane Ube Industries, Ltd. (JP) 2007-07-11 EP disclosed
US-20070129530-A1 Polythiocarbonate polythiol UBE INDUSTRIES, LTD. A CORPORATION OF JAPAN (JP) 2007-06-07 US disclosed
EP-1743912-A1 POLYTHIOURETHANE Ube Industries, Ltd. (JP) 2007-01-17 EP disclosed