Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | POLB | P06746 | 3/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | GFER | P55789 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331618 | 1.00 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL29957473 | 0.99 | ALDH1A1 (0.97) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL29955490 | 0.87 | ALDH1A1 (0.77) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL29956658 | 0.87 | GAA (1.00) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL15330999 | 0.87 | POLB (0.97) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL15331137 | 0.85 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL15330345 | 0.84 | KMT2A (0.76) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL29956904 | 0.79 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL29951842 | 0.79 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1MAPTPOLBGAA | |
| SCHEMBL3955093 | 0.79 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |