Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | POLB | P06746 | 3/20 | 0.77 |
| ▸ | GFER | P55789 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957473 | 0.88 | ALDH1A1 (0.97) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL15331618 | 0.87 | ALDH1A1 (1.00) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL29957359 | 0.87 | ALDH1A1 (1.00) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL15330999 | 0.85 | POLB (0.97) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL29955490 | 0.85 | ALDH1A1 (0.77) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL15331137 | 0.82 | ALDH1A1 (0.73) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL2574902 | 0.82 | GAA (0.69) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL15330345 | 0.81 | KMT2A (0.76) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL29953918 | 0.80 | ALDH1A1 (1.00) | GAAMAPTPOLBGFERALDH1A1 | |
| SCHEMBL2556855 | 0.79 | GAA (1.00) | GAAMAPTPOLBGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |