Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857722 | 1.00 | KDM4E (0.57) | KDM4ELMNAMAPK8RAB9AHSP90AA1 | |
| SCHEMBL13376698 | 0.84 | KDM4E (0.56) | KDM4ELMNAMAPK8RAB9AHSP90AA1 | |
| SCHEMBL1857957 | 0.84 | RAB9A (0.46) | KDM4ELMNARAB9AFGFR4SMN1; SMN2 | |
| SCHEMBL821844 | 0.82 | KDM4E (0.71) | KDM4ELMNAMAPK8RAB9AHSP90AA1 | |
| SCHEMBL9000763 | 0.81 | KDM4E (0.53) | KDM4ELMNAMAPK8RAB9AHSP90AA1 | |
| SCHEMBL1857075 | 0.81 | ADORA1 (0.44) | KDM4ELMNARAB9AFGFR4SMN1; SMN2 | |
| SCHEMBL29951716 | 0.78 | ALDH1A1 (0.44) | KDM4ELMNAMAPK8RAB9AHSP90AA1 | |
| SCHEMBL13596267 | 0.78 | LCK (0.41) | RAB9AFGFR4MEN1KMT2ACDK5 | |
| SCHEMBL29426670 | 0.78 | LCK (0.41) | RAB9AFGFR4MEN1KMT2ACDK5 | |
| SCHEMBL20588932 | 0.77 | KCNH2 (0.44) | FGFR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |