Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782002 | 1.00 | KDM1A (0.42) | KDM1AGPR84CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL2088788 | 0.85 | MAOA (0.43) | KDM1AGPR84CYP11B1CYP11B2HTR1A | |
| SCHEMBL29905104 | 0.85 | MAOA (0.43) | KDM1AGPR84CYP11B1CYP11B2HTR1A | |
| SCHEMBL5865033 | 0.73 | HTR2A (0.35) | KDM1ADRD2HTR2AHTR2CDRD3 | |
| SCHEMBL24386545 | 0.71 | KDM1A (0.46) | KDM1AGPR84CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1842889 | 0.71 | KDM1A (0.46) | KDM1AGPR84CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL15319224 | 0.70 | CYP11B1 (0.47) | KDM1ACYP11B1CYP11B2CYP19A1DRD2 | |
| SCHEMBL5780342 | 0.67 | ENPP2 (0.43) | CYP19A1DRD2DRD3ORAI1ORAI2 | |
| SCHEMBL4623181 | 0.67 | KDM1A (0.50) | KDM1AGPR84CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL10419760 | 0.67 | KDM1A (0.46) | KDM1AGPR84CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |