Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 5/20 | 0.39 |
| ▸ | PSMC4 | P43686 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331156 | 0.88 | RIPK2 (0.46) | SRCABL1SMN1; SMN2PTGS2HPGD | |
| SCHEMBL15332148 | 0.87 | RIPK2 (0.43) | SRCABL1SMN1; SMN2PTGS2HPGD | |
| SCHEMBL15331643 | 0.86 | CYP1A2 (0.39) | SRCABL1PTGS2RIPK2CYP1A2 | |
| SCHEMBL2557902 | 0.85 | ALDH1A1 (0.44) | SRCABL1SMN1; SMN2PTGS2LMNA | |
| SCHEMBL15333135 | 0.85 | PTGS2 (0.40) | SRCABL1SMN1; SMN2PTGS2HPGD | |
| SCHEMBL15331376 | 0.85 | ALDH1A1 (0.36) | SRCABL1SMN1; SMN2HPGDLMNA | |
| SCHEMBL15332052 | 0.85 | RIPK2 (0.51) | SRCABL1SMN1; SMN2PTGS2LMNA | |
| SCHEMBL15331969 | 0.84 | SMN1; SMN2 (0.45) | SRCABL1SMN1; SMN2PTGS2LMNA | |
| SCHEMBL15331051 | 0.84 | TYR (0.38) | SRCABL1SMN1; SMN2PTGS2HPGD | |
| SCHEMBL15332491 | 0.84 | RIPK2 (0.37) | SRCABL1PTGS2ALDH1A1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |