Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331426 | 0.91 | NPBWR1 (0.38) | PIK3CDNPBWR1MCHR1MDM4MDM2 | |
| SCHEMBL29954155 | 0.85 | MAPT (0.38) | MDM4MDM2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15330699 | 0.85 | KMT2A (0.45) | MAPTALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL15330475 | 0.84 | KMT2A (0.45) | NPBWR1MCHR1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2553728 | 0.83 | NPBWR1 (0.42) | PIK3CDNPBWR1MCHR1MAPTALDH1A1 | |
| SCHEMBL15330943 | 0.81 | DHODH (0.41) | PIK3CDMAPTMEN1KMT2A | |
| SCHEMBL2558320 | 0.81 | NPBWR1 (0.37) | NPBWR1MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL15332201 | 0.81 | NPBWR1 (0.40) | NPBWR1MCHR1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29956884 | 0.81 | SMN1; SMN2 (0.47) | MAPTALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL15332268 | 0.79 | DRD2 (0.39) | NPBWR1MCHR1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |