Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3108377 | 1.00 | AGBL2 (0.40) | AGBL2ALDH1A1PLAUMGLLSMN1; SMN2 | |
| SCHEMBL29955314 | 0.82 | AGBL2 (0.41) | AGBL2ALDH1A1PLAUMGLLSMN1; SMN2 | |
| SCHEMBL1922790 | 0.79 | ALDH1A1 (0.45) | AGBL2ALDH1A1PLAUSMN1; SMN2MAPK1 | |
| SCHEMBL29957188 | 0.79 | ALDH1A1 (0.41) | AGBL2ALDH1A1PLAUMGLLSMN1; SMN2 | |
| SCHEMBL2557968 | 0.78 | ALDH1A1 (0.36) | AGBL2ALDH1A1PLAUMGLLSMN1; SMN2 | |
| SCHEMBL29953834 | 0.77 | AGBL2 (0.37) | AGBL2ALDH1A1PLAUSMN1; SMN2MAPK1 | |
| SCHEMBL2634295 | 0.77 | CYP1A2 (0.41) | AGBL2ALDH1A1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL17987938 | 0.75 | AGBL2 (0.49) | AGBL2ALDH1A1PLAUSMN1; SMN2MAPK1 | |
| SCHEMBL3576871 | 0.75 | AGBL2 (0.35) | AGBL2 | |
| SCHEMBL29955213 | 0.75 | AGBL2 (0.35) | AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |