Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663339 | 1.00 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPK1LMNAERCC1 | |
| SCHEMBL6881856 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1LMNAERCC1 | |
| SCHEMBL6881861 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPK1LMNAERCC1 | |
| SCHEMBL5934873 | 0.81 | NOTUM (0.57) | ALDH1A1KDM4EMAPK1LMNAERCC1 | |
| SCHEMBL98459 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPK1NOTUMMEN1 | |
| Hydrochloric Acid SCHEMBL6006151 | 0.79 | NOTUM (0.55) | ALDH1A1KDM4EMAPK1LMNAERCC1 | |
| SCHEMBL4536618 | 0.78 | NOTUM (0.63) | ALDH1A1KDM4EMAPK1NOTUMFGFR1 | |
| SCHEMBL6189574 | 0.78 | KDM4E (0.60) | ALDH1A1KDM4EMAPK1LMNAERCC1 | |
| SCHEMBL17821045 | 0.78 | KDM4E (0.60) | ALDH1A1KDM4EMAPK1LMNAERCC1 | |
| SCHEMBL173839 | 0.77 | NOTUM (0.63) | ALDH1A1KDM4EMAPK1LMNAERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356680-B | Selective inhibitors of NLRP3 inflammasome | 诺瑟拉有限公司 | 2023-11-28 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |