Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410050 | 0.84 | KDM4E (0.72) | ALDH1A1KDM4EMAPK1NOTUMMAPT | |
| SCHEMBL10653293 | 0.84 | KDM4E (0.72) | ALDH1A1KDM4EMAPK1NOTUMMAPT | |
| SCHEMBL4341894 | 0.83 | NOTUM (0.78) | ALDH1A1KDM4EMAPK1NOTUMMAPT | |
| SCHEMBL19979604 | 0.82 | KDM4E (0.70) | ALDH1A1KDM4EMAPK1NOTUMMAPT | |
| SCHEMBL6871245 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPK1NOTUMSMN1; SMN2 | |
| SCHEMBL6850578 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPK1NOTUMSMN1; SMN2 | |
| SCHEMBL13221930 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPK1NOTUMMAPT | |
| SCHEMBL27566874 | 0.81 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPK1NOTUMSMN1; SMN2 | |
| SCHEMBL29957504 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPK1NOTUMMAPT | |
| SCHEMBL1663339 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPK1NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005619-A | Process for producing heterocyclic compound | 武田药品工业株式会社 | 2024-05-10 | — | — | CN | claimed |
| CN-110753689-B | Process for producing heterocyclic compound | 武田药品工业株式会社 | 2024-01-26 | — | — | CN | claimed |
| CN-117024304-A | Preparation method of N ', N' -diaryl hydrazide compound | 赣南师范大学 | 2023-11-10 | — | — | CN | claimed |
| CN-113511977-B | Method for preparing alpha-branched secondary amine compound by adopting photocatalytic multi-component Petasis reaction | 哈尔滨工业大学（深圳） | 2023-03-31 | — | — | CN | claimed |
| CN-113511977-A | Method for preparing alpha-branched secondary amine compound by adopting photocatalytic multi-component Petasis reaction | 哈尔滨工业大学（深圳） | 2021-10-19 | — | — | CN | claimed |
| US-10710989-B2 | Method for producing heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-07-14 | — | — | US | claimed |
| CN-110753689-A | Process for producing heterocyclic compound | 武田药品工业株式会社 | 2020-02-04 | — | — | CN | claimed |
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
| WO-2025095751-A1 | NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME | 현대약품 주식회사 | 2025-05-08 | — | — | WO | disclosed |
| CN-119735563-A | Thiazolidinones as NLRP3 protein inhibitors | 润药仁智(北京)科技有限公司 | 2025-04-01 | — | — | CN | disclosed |
| US-20250011330-A1 | Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors | LEIDOS BIOMEDICAL RESEARCH INC. | 2025-01-09 | — | — | US | disclosed |
| US-20240398783-A1 | Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof | GISMO THERAPEUTICS, INC. | 2024-12-05 | — | — | US | disclosed |
| US-12156871-B2 | Substituted azacycles as muscarinic M1 receptor positive allosteric modulators | SUVEN LIFE SCIENCES LIMITED (IN) | 2024-12-03 | — | — | US | disclosed |
| WO-2002046204-A1 | 6-0-CARBAMOYL KETOLIDE DERIVATIVES OF ERYTHROMYCIN USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-06-13 | — | — | WO | disclosed |
| CN-1275123-A | Prostaglandin agonists and their use to treat bone disorders | PFIZER (US) | 2000-11-29 | — | — | CN | disclosed |
| EP-1021410-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999019300-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 1999-04-22 | — | — | WO | disclosed |
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | ALDH1A1 290/4885KDM4E 3207/4885MAPK1 4269/4885 |
| US-20240398783-A1 | Compounds and Pharmaceutical Compositions Comprising Inhibitors of Amyloid Peptide Interactions with Glycosaminoglycans, Methods of Treatment and Use Thereof | PRNP, GBA1, GBA3 | ALDH1A1 3486/4885KDM4E 4729/4885MAPK1 2880/4885 |
| US-12156871-B2 | Substituted azacycles as muscarinic M1 receptor positive allosteric modulators | CHRM1, CHRM2, CHRM5 | ALDH1A1 3002/4885KDM4E 1995/4885MAPK1 509/4885 |
| US-20250011330-A1 | Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors | TDP1, TDP2, TOP1 | ALDH1A1 769/4885KDM4E 1381/4885MAPK1 986/4885 |
| US-10710989-B2 | Method for producing heterocyclic compound | APP, THOP1, TALDO1 | ALDH1A1 318/4885KDM4E 2271/4885MAPK1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.