Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586420 | 0.77 | AR (0.43) | ADORA2AADORA1NT5EADRB2TLR7 | |
| SCHEMBL431762 | 0.77 | ADORA2A (0.43) | ADORA2AADORA1NT5EADRB2TLR7 | |
| SCHEMBL31074334 | 0.77 | ADORA2A (0.43) | ADORA2AADORA1NT5EADRB2TLR7 | |
| SCHEMBL11126340 | 0.77 | AR (0.43) | ADORA2AADORA1NT5EADRB2TLR7 | |
| SCHEMBL30106725 | 0.75 | BACE1 (0.47) | ADORA2AADORA1NT5EADRB2TLR7 | |
| SCHEMBL29958192 | 0.75 | HTR3A (0.34) | — | |
| SCHEMBL29213933 | 0.75 | ADORA2A (0.44) | ADORA2AADORA1NT5EADRB2TLR7 | |
| SCHEMBL29955050 | 0.75 | ALDH1A1 (0.49) | KMT2A | |
| SCHEMBL2652276 | 0.75 | ALDH1A1 (0.49) | KMT2A | |
| SCHEMBL30586452 | 0.75 | NT5E (0.42) | ADORA2AADORA1NT5EADRB2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |