Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.44 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953893 | 0.79 | KDM1A (0.52) | HTR2CTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL15329847 | 0.79 | KDM1A (0.52) | HTR2CTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL29952551 | 0.75 | HRH3 (0.45) | KDM1AMAOBMAOA | |
| SCHEMBL29954843 | 0.75 | HTR2A (0.44) | HTR2CTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL29954166 | 0.74 | MAOB (0.48) | HTR2CKDM1AMAOBMAOARCOR1 | |
| SCHEMBL1722128 | 0.74 | MAOB (0.48) | HTR2CKDM1AMAOBMAOARCOR1 | |
| SCHEMBL1781688 | 0.74 | MAOB (0.48) | HTR2CKDM1AMAOBMAOARCOR1 | |
| SCHEMBL12813765 | 0.72 | KDM1A (0.63) | HTR2CKDM1AMAOBMAOARCOR1 | |
| SCHEMBL21153832 | 0.72 | HTR2C (0.55) | HTR2CKDM1AMAOBMAOARCOR1 | |
| SCHEMBL12813766 | 0.72 | KDM1A (0.63) | HTR2CKDM1AMAOBMAOARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |