Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | HTR2C | P28335 | 7/20 | 0.48 |
| ▸ | KDM1A | O60341 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781688 | 1.00 | MAOB (0.48) | MAOBMAOAHTR2CKDM1ACYP2C19 | |
| SCHEMBL1722128 | 1.00 | MAOB (0.48) | MAOBMAOAHTR2CKDM1ACYP2C19 | |
| SCHEMBL29953893 | 0.78 | KDM1A (0.52) | HTR2CKDM1ASLC6A2SLC6A3HTR2B | |
| SCHEMBL29954843 | 0.78 | HTR2A (0.44) | HTR2CCYP2C19CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL9817364 | 0.77 | MEN1 (0.50) | MAOBMAOAHTR2CKDM1ACYP2C19 | |
| SCHEMBL10489495 | 0.77 | MEN1 (0.50) | MAOBMAOAHTR2CKDM1ACYP2C19 | |
| SCHEMBL9817367 | 0.77 | MEN1 (0.50) | MAOBMAOAHTR2CKDM1ACYP2C19 | |
| SCHEMBL29957110 | 0.77 | CYP2A6 (0.58) | KDM1ACYP2A6 | |
| SCHEMBL29954593 | 0.77 | HTR2A (0.51) | HTR2CKDM1ASLC6A2SLC6A3RCOR1 | |
| SCHEMBL149599 | 0.77 | KDM1A (0.58) | HTR2CKDM1ASLC6A3RCOR1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |