Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953893 | 0.79 | KDM1A (0.52) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL15329847 | 0.79 | KDM1A (0.52) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL1722128 | 0.78 | MAOB (0.48) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL1781688 | 0.78 | MAOB (0.48) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL29954166 | 0.78 | MAOB (0.48) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL29950949 | 0.76 | KDM1A (0.36) | — | |
| SCHEMBL29957529 | 0.75 | HTR2C (0.49) | HTR2CORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL3673574 | 0.70 | HTR2A (0.52) | HTR2AHTR2CHTR2BALDH1A1CYP1A2 | |
| SCHEMBL29953508 | 0.69 | CHRNB2 (0.50) | ALDH1A1 | |
| SCHEMBL5729182 | 0.69 | KDM1A (0.60) | HTR2CCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |