Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.67 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.51 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.50 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954917 | 0.92 | NOTUM (0.78) | NOTUMTTR | |
| SCHEMBL29954991 | 0.83 | NOTUM (0.65) | NOTUMSERPINE1TTR | |
| SCHEMBL5799674 | 0.83 | NOTUM (0.65) | NOTUMSERPINE1TTR | |
| SCHEMBL27665161 | 0.82 | ALDH1A1 (0.53) | NOTUM | |
| SCHEMBL613069 | 0.82 | ALDH1A1 (0.53) | NOTUM | |
| SCHEMBL3436333 | 0.79 | NOTUM (0.60) | NOTUMSLC6A1 | |
| SCHEMBL7444262 | 0.79 | NOTUM (0.60) | NOTUMSLC6A1 | |
| SCHEMBL2558871 | 0.77 | NPC1 (0.61) | NOTUMSLC6A1 | |
| SCHEMBL29950827 | 0.77 | NOTUM (0.57) | NOTUMSLC6A1 | |
| SCHEMBL15330773 | 0.77 | NOTUM (0.57) | NOTUMSLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |