Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 18/20 | 0.78 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957567 | 0.92 | NOTUM (0.67) | NOTUMTTR | |
| SCHEMBL29954991 | 0.91 | NOTUM (0.65) | NOTUMTTR | |
| SCHEMBL5799674 | 0.91 | NOTUM (0.65) | NOTUMTTR | |
| SCHEMBL14125452 | 0.81 | NOTUM (1.00) | NOTUM | |
| SCHEMBL2934956 | 0.80 | NOTUM (0.65) | NOTUM | |
| SCHEMBL22807134 | 0.79 | RBP4 (0.53) | NOTUMTTR | |
| SCHEMBL1410314 | 0.79 | NOTUM (0.50) | NOTUMTTRHSD11B1 | |
| SCHEMBL3436352 | 0.78 | NOTUM (0.72) | NOTUM | |
| SCHEMBL1704630 | 0.78 | NOTUM (0.72) | NOTUM | |
| SCHEMBL19527509 | 0.78 | NOTUM (0.49) | NOTUMTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |