Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 10/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18368406 | 0.80 | HSD17B3 (0.43) | HSD17B3NOTUMPARP1KDM4EHTT | |
| SCHEMBL20468587 | 0.79 | PARP1 (0.58) | PARP1PARP2HTT | |
| SCHEMBL29955619 | 0.79 | PARP1 (0.58) | PARP1PARP2HTT | |
| SCHEMBL29951234 | 0.75 | NOTUM (0.45) | HSD17B3NOTUMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL29951126 | 0.75 | PARP1 (0.39) | PARP1PARP2KDM4EHTT | |
| SCHEMBL29957680 | 0.75 | PARP1 (0.48) | PARP1PARP2HTT | |
| SCHEMBL29956327 | 0.74 | NPC1 (0.53) | PARP1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL2558999 | 0.73 | PARP1 (0.60) | PARP1PARP2HTT | |
| SCHEMBL29953327 | 0.73 | PARP1 (0.63) | PARP1PARP2KDM4EHTTSMN1; SMN2 | |
| SCHEMBL29957144 | 0.72 | PARP1 (0.42) | PARP1PARP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |