Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951975 | 0.79 | POLB (0.38) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29957027 | 0.75 | HTT (0.44) | MEN1KMT2AHTT | |
| SCHEMBL29951946 | 0.75 | IDH1 (0.44) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29957631 | 0.75 | HSD17B3 (0.44) | NOTUMKDM4EHTTSMN1; SMN2HSD17B3 | |
| SCHEMBL29951915 | 0.74 | UGCG (0.58) | MEN1KMT2AHTTSMN1; SMN2CYP2D6 | |
| SCHEMBL2558098 | 0.73 | PARP1 (0.41) | KDM4EMEN1KMT2AHTT | |
| SCHEMBL29954152 | 0.73 | HTT (0.43) | KDM4EMEN1KMT2AALDH1A1HTT | |
| SCHEMBL29956559 | 0.72 | HRH3 (0.40) | KDM4EMEN1KMT2AALDH1A1HTT | |
| SCHEMBL31373871 | 0.71 | KDM4E (0.59) | NOTUMKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL24874051 | 0.71 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |