Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3179154 | 1.00 | HTR3E (0.51) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL18962466 | 0.77 | HTR1D (0.55) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL29162324 | 0.73 | HTR3E (0.51) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL2885649 | 0.72 | HTR3E (0.48) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL980263 | 0.69 | HTR3E (0.48) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL3197588 | 0.68 | MTNR1A (0.46) | HTR1AHTR2BALDH1A1MAPTNPSR1 | |
| SCHEMBL25359518 | 0.68 | HTR1D (0.54) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL20970981 | 0.68 | HTR1D (1.00) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL1973248 | 0.68 | HTR3E (0.54) | HTR3EHTR3BHTR1AHTR1DHTR1B | |
| SCHEMBL9319102 | 0.68 | SMN1; SMN2 (0.60) | HTR3EHTR3BHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |