Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5851883 | 1.00 | FFAR1 (0.50) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL29952320 | 0.83 | ALDH1A1 (0.46) | FFAR1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL5837673 | 0.83 | HTT (0.41) | KMT2AMAPTHTTALDH1A1GAA | |
| SCHEMBL30716693 | 0.82 | CES2 (0.37) | CES2TP53NFE2L2ALDH1A1BCHE | |
| SCHEMBL4833791 | 0.82 | CES2 (0.37) | CES2TP53NFE2L2ALDH1A1BCHE | |
| SCHEMBL5851624 | 0.80 | MAPT (0.44) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL29952039 | 0.80 | MAPT (0.44) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL571272 | 0.80 | EGFR (0.40) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL4473496 | 0.80 | NPY2R (0.36) | MAPTTP53HTTBCHEACHE | |
| SCHEMBL408195 | 0.78 | NPY2R (0.47) | MEN1KMT2ANPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |