SCHEMBL29957723

SCHEMBL29957723

OB(O)c1cncc(Cl)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.32
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1866579 0.81 CYP3A4 (0.32) CYP3A4
SCHEMBL29956350 0.79 PLAU (0.32) ADRB2MAPT
SCHEMBL29953087 0.76 PDE4D (0.39)
SCHEMBL29957488 0.74 ENPP2 (0.41) CYP3A4
SCHEMBL29957941 0.72 GAA (0.32) ADRB2
SCHEMBL2175515 0.70 GAA (0.41)
SCHEMBL115776 0.70 GAA (0.46) MAPTCYP3A4
Water SCHEMBL3232497 0.68 GAA (0.45) MAPTCYP3A4
Water SCHEMBL452432 0.68 GAA (0.45) MAPTCYP3A4
Water SCHEMBL29955700 0.68 GAA (0.45) MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed