SCHEMBL29956350

SCHEMBL29956350

Cc1c(Cl)cncc1B(O)O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.32
ADRB2 P07550 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957723 0.79 ADRB2 (0.32) ADRB2MAPT
SCHEMBL70682 0.77
SCHEMBL26521598 0.76 CCR1 (0.30)
SCHEMBL1866579 0.74 CYP3A4 (0.32)
SCHEMBL29953087 0.74 PDE4D (0.39)
SCHEMBL20604695 0.73
SCHEMBL432991 0.73 CYP11B2 (0.33)
SCHEMBL15108814 0.71
SCHEMBL29956898 0.71
SCHEMBL5643512 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed