Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.37 |
| ▸ | KDM6B | O15054 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690224 | 1.00 | KDM4C (0.37) | KDM4CKDM6BTSHRPREPFAP | |
| SCHEMBL22684071 | 0.81 | KDM5A (0.39) | KDM4CKDM6BKDM4EALDH1A1TDP1 | |
| SCHEMBL22489729 | 0.77 | LMNA (0.42) | KDM4CKDM6BTSHRHPGDKDM4E | |
| SCHEMBL5787508 | 0.76 | SIRT3 (0.37) | KDM4CKDM6BTSHRHPGDNPSR1 | |
| SCHEMBL1477106 | 0.76 | P2RX4 (0.47) | TSHRHPGDNPSR1MCOLN3KDM4E | |
| SCHEMBL22684034 | 0.75 | KDM4C (0.55) | KDM4CKDM6BKDM4EALDH1A1TDP1 | |
| SCHEMBL29955427 | 0.75 | KDM4C (0.55) | KDM4CKDM6BKDM4EALDH1A1TDP1 | |
| SCHEMBL26258433 | 0.75 | KDM4C (0.42) | KDM4CKDM6BKDM4EALDH1A1TDP1 | |
| SCHEMBL8828511 | 0.75 | ROCK2 (0.47) | KDM4CKDM6BTSHRTDP1SIRT3 | |
| SCHEMBL15906582 | 0.73 | TSHR (0.39) | KDM4CKDM6BTSHRHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |