Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618933 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRSMN1; SMN2CYP2A6 | |
| SCHEMBL7999555 | 0.79 | CYP2A6 (0.33) | ALDH1A1SMN1; SMN2CYP2A6KDM4E | |
| SCHEMBL1619663 | 0.78 | CYP1A2 (0.41) | ALDH1A1LMNATSHRSMN1; SMN2CYP2A6 | |
| SCHEMBL24435029 | 0.78 | CYP1A2 (0.36) | ALDH1A1LMNASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL2567300 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNATSHRSMN1; SMN2CYP2A6 | |
| SCHEMBL29953912 | 0.74 | SRC (0.36) | ALDH1A1LMNACYP2A6 | |
| SCHEMBL3698437 | 0.73 | LMNA (0.50) | ALDH1A1LMNATSHRSMN1; SMN2CYP2A6 | |
| SCHEMBL18205535 | 0.73 | LMNA (0.39) | ALDH1A1LMNATSHRSMN1; SMN2KDM4E | |
| SCHEMBL1901364 | 0.71 | LMNA (0.38) | ALDH1A1LMNATSHRSMN1; SMN2KDM4E | |
| SCHEMBL13485730 | 0.71 | PDE2A (0.38) | ALDH1A1LMNASMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |