Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11997384 | 0.70 | TDP1 (0.48) | MAPTNPC1MAPK1L3MBTL1TDP1 | |
| SCHEMBL27942207 | 0.70 | APEX1 (0.57) | TSHRCYP3A4MAPTNPC1MAPK1 | |
| SCHEMBL6015905 | 0.70 | — | — | |
| SCHEMBL13883997 | 0.69 | GPR35 (0.57) | TSHRCYP3A4MAPTL3MBTL1TDP1 | |
| SCHEMBL6973758 | 0.69 | CYP1A2 (0.47) | TSHRCYP3A4MAPTTDP1ALDH5A1 | |
| SCHEMBL29953071 | 0.69 | GRIA1 (0.41) | TSHRNPC1TDP1ALDH1A1KDM4E | |
| SCHEMBL9376057 | 0.68 | ERN1 (0.44) | MAPTNPC1L3MBTL1ALDH5A1ABAT | |
| SCHEMBL1202546 | 0.68 | TSHR (0.45) | TSHRCYP3A4MAPTNPC1MAPK1 | |
| SCHEMBL949051 | 0.68 | MAPT (0.46) | TSHRCYP3A4MAPTNPC1MAPK1 | |
| SCHEMBL11221923 | 0.68 | TSHR (0.46) | TSHRCYP3A4MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |