Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951120 | 0.78 | — | — | |
| SCHEMBL6015905 | 0.78 | — | — | |
| SCHEMBL29953989 | 0.73 | ERN1 (0.39) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL29955971 | 0.71 | ALDH1A1 (0.42) | ERN1ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL20159038 | 0.70 | ALOX15 (0.43) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL8087354 | 0.70 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL29957791 | 0.69 | TSHR (0.42) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL7328512 | 0.67 | RAB9A (0.66) | ALDH1A1TSHRSMN1; SMN2TDP1KDM4E | |
| SCHEMBL6089194 | 0.67 | MAPT (0.36) | CYP2A6ALDH1A1TDP1KDM4ELMNA | |
| SCHEMBL8163576 | 0.67 | CYP2A6 (0.38) | GRIA1GRIA2GRIA3GRIA4ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |