Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.39 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954507 | 0.94 | CA1 (0.55) | CA1CA2ENPP2UGT2B7MGLL | |
| SCHEMBL2643181 | 0.82 | CA2 (0.61) | CA1CA2ENPP2UGT2B7ALDH1A1 | |
| SCHEMBL28784898 | 0.81 | CA2 (0.76) | CA1CA2ENPP2MGLLTTR | |
| SCHEMBL6816249 | 0.81 | UGT2B7 (0.44) | UGT2B7TSHR | |
| SCHEMBL1714193 | 0.77 | ENPP2 (0.48) | CA1CA2ENPP2MGLLKDM4E | |
| SCHEMBL13667343 | 0.74 | CA2 (0.73) | CA1CA2ENPP2TTRKDM4E | |
| SCHEMBL5096934 | 0.74 | ENPP2 (0.50) | CA1CA2ENPP2MGLLKDM4E | |
| SCHEMBL5782170 | 0.74 | CA1 (0.59) | CA1CA2ENPP2MGLLTTR | |
| SCHEMBL29956090 | 0.74 | CA1 (0.59) | CA1CA2ENPP2MGLLTTR | |
| SCHEMBL205203 | 0.73 | CA2 (0.80) | CA1CA2ENPP2TTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |