Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113494 | 0.81 | ERN1 (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2CYP2A6 | |
| SCHEMBL4279370 | 0.78 | CYP2A6 (0.40) | KDM4EMEN1KMT2ACYP2A6 | |
| SCHEMBL31501965 | 0.77 | CYP2A6 (0.37) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL26660799 | 0.77 | CYP2A6 (0.37) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL29445889 | 0.76 | KEAP1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2AHR | |
| SCHEMBL22407975 | 0.76 | KEAP1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2AHR | |
| SCHEMBL27566870 | 0.75 | KMT2A (0.44) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL5829531 | 0.75 | KMT2A (0.52) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL29953511 | 0.75 | L3MBTL1 (0.45) | SMN1; SMN2MEN1KMT2ACYP2A6MAPT | |
| SCHEMBL29953479 | 0.75 | CYP2A6 (0.38) | ALDH1A1KDM4EMEN1KMT2ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |