Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340510 | 1.00 | PYCR1 (0.42) | PYCR1KDM1AAKR1B1PDPK1NAAA | |
| SCHEMBL29952873 | 0.84 | BRD4 (0.37) | PYCR1KDM1ADGAT1KDM1B | |
| SCHEMBL29953521 | 0.79 | IDO1 (0.48) | — | |
| SCHEMBL29954678 | 0.76 | HTR2A (0.39) | — | |
| SCHEMBL12245651 | 0.76 | HTR2A (0.39) | — | |
| SCHEMBL10168080 | 0.76 | PYCR1 (0.42) | PYCR1 | |
| SCHEMBL12340709 | 0.76 | PYCR1 (0.44) | PYCR1 | |
| SCHEMBL12340877 | 0.76 | KDM1A (0.39) | KDM1A | |
| SCHEMBL12340741 | 0.74 | SMN1; SMN2 (0.36) | PYCR1RAB9A | |
| SCHEMBL20465750 | 0.74 | PYCR1 (0.47) | PYCR1KDM1AAKR1B1PDPK1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |