Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340510 | 0.84 | PYCR1 (0.42) | PYCR1DGAT1KDM1AKDM1B | |
| SCHEMBL29958026 | 0.84 | PYCR1 (0.42) | PYCR1DGAT1KDM1AKDM1B | |
| SCHEMBL29956866 | 0.79 | PSEN1 (0.40) | DPP4 | |
| SCHEMBL29951193 | 0.78 | MEN1 (0.38) | POLB | |
| SCHEMBL12340741 | 0.74 | SMN1; SMN2 (0.36) | PYCR1POLB | |
| SCHEMBL29137937 | 0.74 | DPP4 (0.41) | BRD4BRD2BRD3BRDTDPP4 | |
| SCHEMBL138081 | 0.74 | DPP4 (0.41) | BRD4BRD2BRD3BRDTDPP4 | |
| SCHEMBL1106603 | 0.72 | CCR5 (0.45) | BRD4BRD2BRD3BRDTDPP4 | |
| SCHEMBL135165 | 0.72 | PTGDR2 (0.49) | BRD4BRD2BRD3BRDTDPP4 | |
| SCHEMBL20560539 | 0.72 | DPP4 (0.40) | BRD4BRD2BRD3BRDTDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |