SCHEMBL29958083

SCHEMBL29958083

Cc1nc(F)ccc1C=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
TSHR P16473 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
ERN1 O75460 4/20 0.34
MAPT P10636 1/20 0.34
MPI P34949 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GFER P55789 1/20 0.33
HKDC1 Q2TB90 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22074678 1.00 ALDH1A1 (0.38) ALDH1A1TSHRCYP1A2CYP3A4CYP2D6
SCHEMBL29438802 0.79 TDP1 (0.36) ALDH1A1TSHRKDM4EGAAMEN1
SCHEMBL623439 0.79 TDP1 (0.36) ALDH1A1TSHRKDM4EGAAMEN1
SCHEMBL23457254 0.79 APP (0.32)
SCHEMBL29955945 0.76 CYP1A2 (0.41) ALDH1A1TSHRCYP1A2CYP3A4CYP2D6
SCHEMBL1599165 0.76 CYP1A2 (0.41) ALDH1A1TSHRCYP1A2CYP3A4CYP2D6
SCHEMBL31354851 0.76 ERN1 (0.41) KDM4EMEN1KMT2ATDP1LMNA
SCHEMBL23362591 0.76 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL13723997 0.73 NOS2 (0.54) ALDH1A1TSHRCYP1A2CYP3A4CYP2D6
SCHEMBL15239476 0.73 ERN1 (0.42) ALDH1A1TSHRCYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025020886-A1 AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF 浙江星浩澎博医药有限公司 2025-01-30 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed