Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | NEK2 | P51955 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428546 | 0.86 | RECQL (1.00) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7537943 | 0.83 | RECQL (0.76) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7578880 | 0.80 | KEAP1 (0.76) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL164503 | 0.80 | RECQL (0.76) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7573136 | 0.80 | KEAP1 (0.76) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7196466 | 0.79 | KMT2A (0.75) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7536143 | 0.78 | RECQL (0.71) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27499581 | 0.77 | RECQL (0.76) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9942077 | 0.77 | RECQL (0.71) | RECQLKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL163325 | 0.77 | RECQL (0.69) | RECQLKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |