Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.76 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | EP300 | Q09472 | 1/20 | 0.64 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.64 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765236 | 0.90 | KEAP1 (0.86) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL17849555 | 0.88 | KEAP1 (0.62) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL1428546 | 0.86 | RECQL (1.00) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL2055418 | 0.86 | RECQL (0.69) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL28370028 | 0.84 | KEAP1 (0.58) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL30083688 | 0.84 | KEAP1 (0.58) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL2069322 | 0.84 | KEAP1 (0.71) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL2068526 | 0.84 | LMNA (0.82) | KEAP1NFE2L2KMT2AALDH1A1MEN1 | |
| SCHEMBL15248882 | 0.84 | KEAP1 (0.76) | KEAP1NFE2L2RECQLKMT2AALDH1A1 | |
| SCHEMBL7578880 | 0.84 | KEAP1 (0.76) | KEAP1NFE2L2RECQLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542556-B1 | Thermosensitive recording material | NEW OJI PAPER CO LTD (JP) | 1995-07-19 | — | — | EP | claimed |
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |