Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319853 | 1.00 | ENPP2 (0.45) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL1994361 | 0.85 | HSD17B10 (0.46) | ENPP2CA1CA2HSD17B10IDO1 | |
| SCHEMBL28458052 | 0.83 | ENPP2 (0.44) | ENPP2CA1CA2HSD17B10CYP11B1 | |
| SCHEMBL13197059 | 0.80 | GAA (0.50) | ENPP2CA1CA2HSD17B10ABCB11 | |
| SCHEMBL2061056 | 0.79 | KDM4E (0.50) | CA1CA2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28687663 | 0.79 | LIPG (0.53) | — | |
| SCHEMBL4592648 | 0.78 | KDM4E (0.43) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL26768678 | 0.78 | BAZ2B (0.56) | CA1CA2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL20780588 | 0.76 | HTR2A (0.43) | ENPP2CA1CA2HSD17B10ABCB11 | |
| SCHEMBL487944 | 0.76 | HSD17B10 (0.62) | CA1CA2HSD17B10IDO1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |