SCHEMBL29958435

SCHEMBL29958435

CC(C)(C)OOC(=O)/N=C(/NCCc1ccc(CCCF)cc1)NC(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.46
CA1 P00915 5/20 0.46
NAMPT P43490 1/20 0.37
CTSK P43235 3/20 0.37
SIGMAR1 Q99720 2/20 0.34
PTGER4 P35408 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
AKT1 P31749 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18401386 0.91 CA2 (0.49) CA2CA1NAMPTCTSKSIGMAR1
SCHEMBL29958774 0.90 CA2 (0.47) CA2CA1NAMPTCTSKNR1H4
SCHEMBL16208966 0.87 CA2 (0.49) CA2CA1NAMPTCTSKSIGMAR1
SCHEMBL16208965 0.87 CA2 (0.49) CA2CA1NAMPTCTSKSIGMAR1
SCHEMBL12401895 0.84 CA2 (0.53) CA2CA1NAMPTCTSKSIGMAR1
SCHEMBL18401365 0.81 CA2 (0.50) CA2CA1NAMPTCTSKNR1H4
SCHEMBL8381013 0.78 CA2 (0.49) CA2CA1NAMPTCTSK
SCHEMBL15684582 0.78 CA2 (0.49) CA2CA1NAMPTPTGER4
SCHEMBL24670449 0.77 CA2 (0.48) CA2CA1NAMPTCTSKPTGER4
SCHEMBL16208882 0.77 CA2 (0.50) CA2CA1NAMPTCTSKSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 US disclosed
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. 2022-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 CA2 992/4885CA1 85/4885NAMPT 2707/4885
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 CA2 992/4885CA1 85/4885NAMPT 2707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.