Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.57 |
| ▸ | ARG2 | P78540 | 5/20 | 0.52 |
| ▸ | ARG1 | P05089 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599185 | 1.00 | GSR (0.57) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL259006 | 0.98 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL17262412 | 0.98 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL3423971 | 0.98 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL79859 | 0.91 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL198242 | 0.91 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL2722969 | 0.91 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL30463729 | 0.89 | GSR (0.54) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL29624332 | 0.87 | GSR (0.44) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL4956653 | 0.86 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022156764-A1 | COMPOUND FOR DEGRADING DEOXYRIBONUCLEIC ACID (DNA) POLYMERASE, AND USE THEREOF | 泰比棣医药科技(石家庄)有限公司 | 2022-07-28 | — | — | WO | disclosed |