Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 4/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033507 | 1.00 | F2 (0.49) | F2USP2IDH1MASP2MAPT | |
| SCHEMBL29174289 | 0.94 | F2 (0.46) | F2USP2IDH1MASP2MAPT | |
| SCHEMBL1197181 | 0.88 | F2 (0.48) | F2USP2IDH1MASP2MAPT | |
| SCHEMBL30711653 | 0.84 | F11 (0.48) | F2MASP2F11KLKB1CYP3A4 | |
| SCHEMBL27033841 | 0.84 | F11 (0.48) | F2MASP2F11KLKB1CYP3A4 | |
| SCHEMBL27033847 | 0.83 | F2 (0.47) | F2MASP2F11KLKB1CYP3A4 | |
| SCHEMBL30711643 | 0.83 | F2 (0.47) | F2MASP2F11KLKB1CYP3A4 | |
| Lithium Ion SCHEMBL29174316 | 0.82 | F11 (0.46) | F2MASP2F11KLKB1CYP3A4 | |
| Lithium Ion SCHEMBL30711671 | 0.82 | F11 (0.46) | F2MASP2F11KLKB1CYP3A4 | |
| SCHEMBL17232504 | 0.81 | F2 (0.49) | F2IDH1MASP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308228-A1 | PLASMA KALLIKREIN INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022197756-A1 | PLASMA KALLIKREIN INHIBITORS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |