Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 4/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033847 | 1.00 | F2 (0.47) | F2NOTUMMASP2F11KLK1 | |
| SCHEMBL27033841 | 0.88 | F11 (0.48) | F2NOTUMMASP2F11KLK1 | |
| SCHEMBL30711653 | 0.88 | F11 (0.48) | F2NOTUMMASP2F11KLK1 | |
| Lithium Ion SCHEMBL30711671 | 0.85 | F11 (0.46) | F2NOTUMMASP2F11KLK1 | |
| Lithium Ion SCHEMBL29174316 | 0.85 | F11 (0.46) | F2NOTUMMASP2F11KLK1 | |
| SCHEMBL29141797 | 0.83 | F2 (0.45) | F2NOTUMMASP2F11KLKB1 | |
| SCHEMBL27033507 | 0.83 | F2 (0.49) | F2MASP2F11KLK1KLKB1 | |
| SCHEMBL29958713 | 0.83 | F2 (0.49) | F2MASP2F11KLK1KLKB1 | |
| Acetic Acid SCHEMBL3931722 | 0.82 | MASP2 (0.49) | F2MASP2F11KLK1KLKB1 | |
| SCHEMBL24729488 | 0.81 | F2 (0.49) | F2NOTUMMASP2F11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |