Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24191989 | 1.00 | NR1H2 (0.65) | NR1H2ALDH1A1LMNADDR1POLB | |
| SCHEMBL4267414 | 0.84 | CYP2C9 (0.45) | NR1H2ALDH1A1KDM4EABL1ACHE | |
| SCHEMBL24192354 | 0.84 | ALDH1A1 (0.51) | NR1H2ALDH1A1DDR1POLBKDM4E | |
| SCHEMBL2075627 | 0.83 | NR1H2 (0.59) | NR1H2ALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL273351 | 0.79 | NR1H2 (1.00) | NR1H2ALDH1A1LMNADDR1POLB | |
| SCHEMBL24192813 | 0.79 | NR1H2 (0.70) | NR1H2ALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL29493475 | 0.79 | NR1H2 (1.00) | NR1H2ALDH1A1LMNADDR1POLB | |
| SCHEMBL11889095 | 0.78 | CCR5 (0.42) | NR1H2ALDH1A1DDR1POLBMGLL | |
| SCHEMBL15542251 | 0.77 | NR1H2 (0.67) | NR1H2ALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL26644575 | 0.76 | MAPT (0.55) | NR1H2ALDH1A1LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320127-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022226182-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022216680-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-13 | — | — | WO | disclosed |